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Additional analysis was performed to estimate the association of body weight reduction on changes in HOMA2-IR (computed with insulin) with tirzepatide

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Back to Journals Diabetes, Metabolic Syndrome and Obesity Volume 12 Dual GIPGLP1-Receptor Agonists In The Treatment Of Type 2 Diabetes: A Short Review On Emerging Data And Therapeutic Potential Authors Bastin M , Andreelli F Received 12 May 2019 Accepted for publication 17 August 2019 Published 30 September 2019 Volume 2019:12 Pages 19731985 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Konstantinos Tziomalos Marie Bastin, Fabrizio Andreelli Diabetology-Metabolism Department, Sorbonne Universit, ICAN, Assistance Publique Hpitaux de Paris, Piti-Salptrire Hospital, Paris, F-75013, France Correspondence: Fabrizio Andreelli Diabetology-Metabolism Department, Piti-Salptrire Hospital, 47-83 Boulevard de lHpital, Paris cedex 13, 75951, France Email [email protected] Abstract: The need for efficient and safe therapy to improve such metabolic diseases as obesity and type 2 diabetes mellitus is currently unmet

note that tirzepatide is also available as Mounjaro, which holds a separate MHRA authorisation for the treatment of type 2 diabetes these are distinct licensed indications and should not be confused [14] [15] These medicines are supported by robust clinical trial data, have established safety profiles, and are prescribed within regulated frameworks with appropriate monitoring

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Weight loss effects are usually observed within 2-3 months, but it can vary based on individual metabolic rates and lifestyle factors